MaineHealth Let’s Go! Shorts Video Series
Obesity Genetics & Epigenetics | Episode 3
Genes and obesity | CDC
https://www.cdc.gov/genomics/resources/diseases/obesity/obesedit.htm
Genetic Syndromes Associated with Obesity | Clinical Gate
https://clinicalgate.com/genetic-syndromes-associated-with-obesity/
What is Epigenetics? | CDC
https://www.cdc.gov/genomics/disease/epigenetics.htm
Nutrition in the First 1000 Days: Ten Practices to Minimize Obesity Emerging from Published Science | NIH
https://pubmed.ncbi.nlm.nih.gov/29194402/#article-details
0:00 – Welcome
0:41 – Genetics of Obesity
1:24 – Single Gene Defects
2:20 – Genes associated with obesity
2:51 – Genetic syndromes associated with obesity
3:28 – Epigenetics
4:22 – Tale of 2 Siblings
5:10 – Next Steps Video Rating: / 5
Genetic testing is becoming more widely available and affordable, allowing individuals to learn more about their genetic makeup and potential health risks. This has implications for personalized medicine and disease prevention. Advances in genome sequencing technology have made it possible to sequence entire genomes in a matter of days or weeks, providing researchers with unprecedented insights into the genetic basis of disease and other biological processes.
#crispr #DNA #homozygous #genomics #GeneTherapy
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The genetics of obesity.
Recently I have been tagged in a lot of videos from people disregarding the role that genes have when it comes to your body weight.
They often use false dichotomies, like ‘no, it is not your genes, you are eating too much’ which grossly misrepresents the role that genes play.
It isn’t your genes *or* how much you eat, it is more like *how* your genes influence how much you eat.
So, let’s talk about some basic genetic concepts and how they are involved with body weight regulation.
P.S. My new book ‘Everything Fat Loss’ is currently on sale at Amazon with an additional 10% and 22% discount in the .com and .co.uk markets. Feel free to grab it before the price goes up.
References:
– The body-mass index of twins who have been reared apart
– A twin study of human obesity
– New advances in the genetics of early onset obesity
– Positional cloning of the mouse obese gene and its human homologue
– Congenital leptin deficiency is associated with severe early-onset obesity in humans
– Lessons from extreme human obesity: monogenic disorders
– The genetics of obesity: from discovery to biology
– Variability in the heritability of body mass index: a systematic review and meta-regression Video Rating: / 5
In this video, we’ll attempt to answer the question of what causes our personality—that is, why we are the way we are. We’ll discuss several different psychological approaches to answering this question, and we’ll specifically address the extent to which our genetics vs. environments influence our personality.
Monozygotic (MZ) Twins: Twins who share 100% of their genetic material; identical twins.
Dizygotic (DZ) Twins: Twins who share 50% of their genetic material; fraternal twins.
Biological Determinism: The belief that personality traits are inborn.
Social-Cognitive Theory of Personality: Posits that both learning (the focus of behaviorists) as well as cognitive factors are sources of individual differences in personality.
Reciprocal Determinism: The idea that behavior and thought both influence and are influenced by the social environment; the Social-Cognitive Theory of Personality proposes that all of these factors influence each other.
Observational Learning: A vicarious form of learning that is driven by observing someone else’s behavior and its consequences; Social-Cognitive theorists believe that observational learning plays a role in forming personality in that we develop behavior patterns based on our observations of others.
Self-efficacy: The level of confidence we have in our own abilities; influenced by our social experiences (e.g., the feedback we get from others) and affects how we approach future challenges.
Freudian Slip: A slip of the tongue in which we say something we didn’t intend to, presumably because the statement was associated with some thought or urge lingering in the unconscious.
Id: An aspect of personality that consists of our most primitive drives or urges, including impulses for hunger, thirst, and sex.
Superego: An aspect of the personality that serves as one’s moral compass, or conscience.
Ego: An aspect of personality that represents the self, or the part of one’s personality that is visible to others. Video Rating: / 5
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Alistair Campbell explores an interesting perspective on depression.
Alastair is best known for his role as Tony Blair’s formidable and often contentious spin doctor, but, away from the public eye, he has been dogged by crippling bouts of depression for most of his life. Some days, just getting out of bed is too hard. Therapy and anti-depressant medication is helping him keep his head above water, but is that really the best he can hope for?
Encouraged by his family, Alastair sets out on a journey to explore if cutting edge science can offer him – and the millions of people like him – the hope of one day living depression-free. As he tries to understand his depression better, he also reflects on key events in his life and asks if they could have had a negative effect on his mind.
Alistair Campbell: Depression and Me | BBC
#MentalHealthWeek
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All our TV channels and S4C are available to watch live through BBC iPlayer, although some programmes may not be available to stream online due to rights. If you would like to read more on what types of programmes are available to watch live, check the ‘Are all programmes that are broadcast available on BBC iPlayer?’ FAQ 👉 https://bbc.in/2m8ks6v. Video Rating: / 5
Your children’s genes reflect only their potential, not their destiny. It is up to us to provide the environment that allows them to develop to their highest potential. Educate yourself more on your children’s self-discovery on our next episode of Genomy’s Virtual Discussion, “The Influence of Genetics in Child Development”. Video Rating: / 5
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Parents, take a deep breath: how your kids turn out isn’t fully on you. Of course, parenting plays an important role in shaping who children become, but psychologist Yuko Munakata offers an alternative, research-backed reality that highlights how it’s just one of many factors that influence the chaotic complexity of childhood development. A rethink for anyone wondering what made them who they are today and what it means to be a good parent.
0:00 Intro
0:53 Why most parenting advice is wrong
1:50 Hurricane children vs. butterfly parents
2:53 The myth of inherited success (or struggle)
5:25 Can you predict who a child becomes?
8:19 Same event, different experience
9:59 The mystery of parenting
11:45 Stop the blame game
12:56 What you learn parenting terminally ill children
15:10 Why parenting is about staying in the moment
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(April 12, 2010) Robert Sapolsky introduces a two-part series exploring the controversial scientific practice of inferring behavior to genetics. He covers classical techniques in behavior genetics and flaws, the significance of environmental factors, non genetic inheritance of traits, and multigenerational effects and relationship to epigenetic differences.
Stanford University
http://www.stanford.edu
Stanford Department of Biology
http://biology.stanford.edu/
Stanford University Channel on YouTube
http://www.youtube.com/stanford
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This video aims to deliver insightful information regarding our genes and drug addiction, through an entertaining video. Drug addiction is an issue within almost every society in the world. This condition can affect people of all ages regardless of demographic factors such as socioeconomic status. We try to answer how do our genes play a role in addiction.
This video was created by McMaster Demystifying Medicine students Michelle Armstrong, Mohammed Cassim, Tania Namrud, Suraj Brar and Daniela Carvalho
Copyright McMaster University 2019
References:
Figure 1. Addiction Heritability: Bevilacqua, L., & Goldman, D. (2009). Genes and addictions. Clinical pharmacology and therapeutics, 85(4), 359–361. doi:10.1038/clpt.2009.6
Figure 2: Genes vs Environment: Rose, R. J., Dick, D. M., Viken, R. J., Pulkkinen, L., & Kaprio, J. (2004). Genetic and environmental effects on conduct disorder and alcohol dependence symptoms and their covariation at age 14. Alcoholism: Clinical and Experimental Research, 28(10), 1541-1548.
What is addiction? Retrieved from https://www.psychiatry.org/patients-families/addiction/what-is-addiction
National Institute on Drug Abuse. (n.d.). The Science of Drug Use and Addiction: The Basics. Retrieved from https://www.drugabuse.gov/publications/media-guide/science-drug-use-addiction-basics.
What is heritability? – Genetics Home Reference – NIH. (n.d.). Retrieved from https://ghr.nlm.nih.gov/primer/inheritance/heritability.
Goldman, D., Oroszi, G., & Ducci, F. (2006). The Genetics of Addictions: Uncovering the Genes. Focus, 4(3), 401–415. doi: 10.1176/foc.4.3.401 Video Rating: / 5
Moe Saha does away with the notion that mental illness is somehow not a legitimate illness in her talk. She uses her background in the genetic sciences to back up her argument, and make the case for potential new treatments.
Tamoha Saha is a student at Los Altos High School with unusual passions for both genetics and mental health. She has performed lots of personal research on the subjects.
This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at http://ted.com/tedx
