Jonathan Sebat, PhD, Director, Beyster Institute for Psychiatric Genomics, Professor of Psychiatry, Cellular & Molecular Medicine, and Pediatrics, UC San Diego School of Medicine joins William Mobley, MD, PhD to discuss genetics as they relate to autism and how technology can help pinpoint the genes contributing to the disorder. Watch the Entire Talk Here: https://www.youtube.com/watch?v=hjeBM95Nft0&t=15s [11/2017] [Show ID: 33065]

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The genetics of obesity.

Recently I have been tagged in a lot of videos from people disregarding the role that genes have when it comes to your body weight.

They often use false dichotomies, like ‘no, it is not your genes, you are eating too much’ which grossly misrepresents the role that genes play.

It isn’t your genes *or* how much you eat, it is more like *how* your genes influence how much you eat.

So, let’s talk about some basic genetic concepts and how they are involved with body weight regulation.

P.S. My new book ‘Everything Fat Loss’ is currently on sale at Amazon with an additional 10% and 22% discount in the .com and .co.uk markets. Feel free to grab it before the price goes up.

References:
– The body-mass index of twins who have been reared apart
– A twin study of human obesity
– New advances in the genetics of early onset obesity
– Positional cloning of the mouse obese gene and its human homologue
– Congenital leptin deficiency is associated with severe early-onset obesity in humans
– Lessons from extreme human obesity: monogenic disorders
– The genetics of obesity: from discovery to biology
– Variability in the heritability of body mass index: a systematic review and meta-regression
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View full lesson: http://ed.ted.com/lessons/how-the-choices-you-make-can-affect-your-genes-carlos-guerrero-bosagna

Here’s a conundrum: Identical twins originate from the same DNA … so how can they turn out so different — even in traits that have a significant genetic component? Carlos Guerrero-Bosagna explains that while nature versus nurture has a lot to do with it, a deeper, related answer can be found within something called epigenetics.

Lesson by Carlos Guerrero-Bosagna, animation by Chris Bishop.
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